David Komander : rechercher sur Z-Library

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1

Mechanisms of Deubiquitinase Specificity and Regulation

Mevissen, Tycho E.T., Komander, David

Journal:

Annual Review of Biochemistry

Année:

2017

Langue:

english

Fichier:

PDF, 6.79 MB

english, 2017

2

The nuts and bolts of AGC protein kinases

Pearce, Laura R., Komander, David, Alessi, Dario R.

Journal:

Nature Reviews Molecular Cell Biology

Année:

2010

Langue:

english

Fichier:

PDF, 783 KB

english, 2010

3

The Ubiquitin Code

Komander, David, Rape, Michael

Journal:

Annual Review of Biochemistry

Année:

2012

Langue:

english

Fichier:

PDF, 2.00 MB

english, 2012

4

Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure

Komander, David, Garg, Ritu, Wan, Paul T C, Ridley, Anne J, Barford, David

Journal:

The EMBO Journal

Année:

2008

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2008

5

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

Komander, David, Reyes-Turcu, Francisca, Licchesi, Julien D F, Odenwaelder, Peter, Wilkinson, Keith D, Barford, David

Journal:

Année:

2009

Fichier:

PDF, 55 KB

2009

6

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

Komander, David, Reyes-Turcu, Francisca, Licchesi, Julien D F, Odenwaelder, Peter, Wilkinson, Keith D, Barford, David

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2009

7

A further case of Dop-ing in bacterial pupylation

Bremm, Anja, Komander, David

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 243 KB

english, 2010

8

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

Ye, Yu, Akutsu, Masato, Reyes-Turcu, Francisca, Enchev, Radoslav I, Wilkinson, Keith D, Komander, David

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2011

9

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

Virdee, Satpal, Ye, Yu, Nguyen, Duy P, Komander, David, Chin, Jason W

Journal:

Nature Chemical Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2010

10

Breaking the chains: structure and function of the deubiquitinases

Komander, David, Clague, Michael J., Urbé, Sylvie

Journal:

Nature Reviews Molecular Cell Biology

Année:

2009

Langue:

english

Fichier:

PDF, 793 KB

english, 2009

11

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

Kulathu, Yogesh, Akutsu, Masato, Bremm, Anja, Hofmann, Kay, Komander, David

Journal:

Nature Structural and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 571 KB

english, 2009

12

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

Bremm, Anja, Freund, Stefan M V, Komander, David

Journal:

Nature Structural and Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2010

13

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

Safrany, Stephen T, Alessi, Dario R, van Aalten, Daan M F, Komander, David, Fairservice, Alison, Deak, Maria, Kular, Gursant S, Prescott, Alan R, Peter Downes, C

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 550 KB

english, 2004

14

Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

Kulathu, Yogesh, Komander, David

Journal:

Nature Reviews Molecular Cell Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2012

15

Lining the pockets of kinases and phosphatases

Matthew G Gold, David Barford, David Komander

Journal:

Current Opinion in Structural Biology

Année:

2006

Langue:

english

Fichier:

PDF, 3.36 MB

english, 2006

16

Interactions of LY333531 and Other Bisindolyl Maleimide Inhibitors with PDK1

David Komander, Gursant S. Kular, Alexander W. Schüttelkopf, Maria Deak, K.R.C. Prakash, Jennifer Bain, Matthew Elliott, Marta Garrido-Franco, Alan P. Kozikowski, Dario R. Alessi, Daan M.F. van Aalten

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 651 KB

english, 2004

17

Emerging roles for Lys11-linked polyubiquitin in cellular regulation

Anja Bremm, David Komander

Journal:

Trends in Biochemical Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2011

18

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

von Muhlinen, Natalia, Akutsu, Masato, Ravenhill, Benjamin J., Foeglein, Ágnes, Bloor, Stuart, Rutherford, Trevor J., Freund, Stefan M.V., Komander, David, Randow, Felix

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2012

19

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

Simin Rahighi, Fumiyo Ikeda, Masato Kawasaki, Masato Akutsu, Nobuhiro Suzuki, Ryuichi Kato, Tobias Kensche, Tamami Uejima, Stuart Bloor, David Komander, Felix Randow, Soichi Wakatsuki, Ivan Dikic

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2009

20

New Tools for Ubiquitin Signaling

Kirstin Keusekotten, David Komander

Journal:

Journal of Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 93 KB

english, 2012

21

The Structure of the CYLD USP Domain Explains Its Specificity for Lys63-Linked Polyubiquitin and Reveals a B Box Module

David Komander, Christopher J. Lord, Hartmut Scheel, Sally Swift, Kay Hofmann, Alan Ashworth, David Barford

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.80 MB

english, 2008

22

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

Tobias L. Haas, Christoph H. Emmerich, Björn Gerlach, Anna C. Schmukle, Stefanie M. Cordier, Eva Rieser, Rebecca Feltham, James Vince, Uwe Warnken, Till Wenger, Ronald Koschny, David Komander, John Si

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2009

23

CYLD Tidies Up Dishevelled Signaling

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 61 KB

english, 2010

24

PDK1, the master regulator of AGC kinase signal transduction

Alfonso Mora, David Komander, Daan M.F. van Aalten, Dario R. Alessi

Journal:

Seminars in Cell & Developmental Biology

Année:

2004

Langue:

english

Fichier:

PDF, 347 KB

english, 2004

25

Ubiquitin chain conformation regulates recognition and activity of interacting proteins

Ye, Yu, Blaser, Georg, Horrocks, Mathew H., Ruedas-Rama, Maria J., Ibrahim, Shehu, Zhukov, Alexander A., Orte, Angel, Klenerman, David, Jackson, Sophie E., Komander, David

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 884 KB

english, 2012

26

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

Kulathu, Yogesh, Garcia, Francisco J., Mevissen, Tycho E. T., Busch, Martin, Arnaudo, Nadia, Carroll, Kate S., Barford, David, Komander, David

Journal:

Nature Communications

Année:

2013

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2013

27

Assembly, analysis and architecture of atypical ubiquitin chains

Hospenthal, Manuela K, Freund, Stefan M V, Komander, David

Journal:

Nature Structural and Molecular Biology

Année:

2013

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2013

28

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

Licchesi, Julien D F, Mieszczanek, Juliusz, Mevissen, Tycho E T, Rutherford, Trevor J, Akutsu, Masato, Virdee, Satpal, Oualid, Farid El, Chin, Jason W, Ovaa, Huib, Bienz, Mariann, Komander, David

Journal:

Nature Structural and Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2011

29

Molecular Basis and Regulation of OTULIN-LUBAC Interaction

Elliott, Paul R., Nielsen, Sofie V., Marco-Casanova, Paola, Fiil, Berthe Katrine, Keusekotten, Kirstin, Mailand, Niels, Freund, Stefan M.V., Gyrd-Hansen, Mads, Komander, David

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 4.49 MB

english, 2014

30

OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

Fiil, Berthe Katrine, Damgaard, Rune Busk, Wagner, Sebastian Alexander, Keusekotten, Kirstin, Fritsch, Melanie, Bekker-Jensen, Simon, Mailand, Niels, Choudhary, Chunaram, Komander, David, Gyrd-Hansen,

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.60 MB

english, 2013

31

Novel Inositol Phospholipid Headgroup Surrogate Crystallized in the Pleckstrin Homology Domain of Protein Kinase Bα

Mills, Stephen J., Komander, David, Trusselle, Melanie N., Safrany, Stephen T., van Aalten, Daan M. F., Potter, Barry V. L.

Journal:

ACS Chemical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2007

32

Introducing Our Authors

Chong, Curtis R., Xu, Jing, Mills, Stephen J., Komander, David, Puffer, Erik B., Baigude, Huricha, Scheck, Rebecca A.

Journal:

ACS Chemical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 669 KB

english, 2007

33

Dissection of USP catalytic domains reveals five common insertion points

Ye, Yu, Scheel, Hartmut, Hofmann, Kay, Komander, David

Journal:

Molecular BioSystems

Année:

2009

Langue:

english

Fichier:

PDF, 4.24 MB

english, 2009

34

The emerging complexity of protein ubiquitination

Komander, David

Journal:

Biochemical Society Transactions

Année:

2009

Langue:

english

Fichier:

PDF, 972 KB

english, 2009

35

The JAMM in the proteasome

Wauer, Tobias, Komander, David

Journal:

Nature Structural and Molecular Biology

Année:

2014

Langue:

english

Fichier:

PDF, 783 KB

english, 2014

36

Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest)

Hospenthal, Manuela K, Mevissen, Tycho E T, Komander, David

Journal:

Nature Protocols

Année:

2015

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2015

37

Structure of the A20 OTU domain and mechanistic insights into deubiquitination

Komander, David, Barford, David

Journal:

Biochemical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2008

38

An essential role for the ATG8 ortholog LC3C in antibacterial autophagy

von Muhlinen, Natalia, Akutsu, Masato, Ravenhill, Benjamin J., Foeglein, Ágnes, Bloor, Stuart, Rutherford, Trevor J., Freund, Stefan M.V., Komander, David, Randow, Felix

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 802 KB

english, 2013

39

Structure of the human Parkin ligase domain in an autoinhibited state

Wauer, Tobias, Komander, David

Journal:

The EMBO Journal

Année:

2013

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2013

40

Mechanism of phospho-ubiquitin-induced PARKIN activation

Wauer, Tobias, Simicek, Michal, Schubert, Alexander, Komander, David

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 8.27 MB

english, 2015

41

Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin

Michel, Martin A., Elliott, Paul R., Swatek, Kirby N., Simicek, Michal, Pruneda, Jonathan N., Wagstaff, Jane L., Freund, Stefan M.V., Komander, David

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.90 MB

english, 2015

42

Erratum: Mechanism of phospho-ubiquitin-induced PARKIN activation

Wauer, Tobias, Simicek, Michal, Schubert, Alexander, Komander, David

Journal:

Année:

2015

Fichier:

PDF, 28 KB

2015

43

Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

Masato Akutsu, Yu Ye, Satpal Virdee, Jaśon W. Chin, David Komander and J. Wade Harper

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2011

44

Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

Geurink, Paul P., van Tol, Bianca D. M., van Dalen, Duco, Brundel, Paul J. G., Mevissen, Tycho E. T., Pruneda, Jonathan N., Elliott, Paul R., van Tilburg, Gabriëlle B. A., Komander, David, Ovaa, Huib

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2016

45

Ubiquitin modifications

Swatek, Kirby N, Komander, David

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2016

46

Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN

Elliott, Paul R., Komander, David

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2016

47

CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling

Hrdinka, Matous, Fiil, Berthe Katrine, Zucca, Mattia, Leske, Derek, Bagola, Katrin, Yabal, Monica, Elliott, Paul R., Damgaard, Rune Busk, Komander, David, Jost, Philipp J., Gyrd-Hansen, Mads

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.62 MB

english, 2016

48

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

Flierman, Dennis, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Geurink, Paul P., Mevissen, Tycho E.T., Hospenthal, Manuela K., Komander, David, Ovaa, Huib

Journal:

Cell Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2016

49

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

Pruneda, Jonathan N., Durkin, Charlotte H., Geurink, Paul P., Ovaa, Huib, Santhanam, Balaji, Holden, David W., Komander, David

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 5.97 MB

english, 2016

50

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

Damgaard, Rune Busk, Walker, Jennifer A., Marco-Casanova, Paola, Morgan, Neil V., Titheradge, Hannah L., Elliott, Paul R., McHale, Duncan, Maher, Eamonn R., McKenzie, Andrew N.J., Komander, David

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 10.65 MB

english, 2016